Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485131 | 0.75 | CHRNB2 (0.36) | — | |
| SCHEMBL8487415 | 0.70 | SLC6A3 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8487483 | 0.68 | MDM2 (0.39) | HTR2CSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL8489231 | 0.66 | CHRNB2 (0.37) | — | |
| SCHEMBL11625518 | 0.64 | MAOB (0.49) | HTR2CMAOAMAOBHTR2AHTR2B | |
| SCHEMBL1565213 | 0.62 | — | — | |
| Iodide SCHEMBL11747618 | 0.62 | MAOB (0.47) | HTR2CMAOAMAOBHTR2AHTR2B | |
| SCHEMBL5598888 | 0.62 | MAOB (0.47) | HTR2CMAOAMAOBDDB1CRBN | |
| SCHEMBL8207826 | 0.62 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL16558109 | 0.62 | HTR2C (0.34) | HTR2CSLC6A2SLC6A4SLC6A3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |