Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486111 | 1.00 | IDO1 (0.40) | IDO1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8486118 | 1.00 | IDO1 (0.40) | IDO1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8921833 | 0.83 | HTR2A (0.39) | IDO1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL8488193 | 0.81 | ALDH1A1 (0.36) | HTR2AHTR2CHTR2BHRH3TSHR | |
| SCHEMBL8488189 | 0.81 | ALDH1A1 (0.36) | HTR2AHTR2CHTR2BHRH3TSHR | |
| SCHEMBL8488183 | 0.81 | ALDH1A1 (0.36) | HTR2AHTR2CHTR2BHRH3TSHR | |
| SCHEMBL7375443 | 0.75 | MAPT (0.49) | IDO1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4988928 | 0.75 | IDO1 (0.46) | IDO1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18552441 | 0.75 | MAPT (0.49) | IDO1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7927054 | 0.75 | IDO1 (0.45) | IDO1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977355-A | Processes and intermediates for preparing 3-amino-benzo(b)azepinones | PFIZER INC. (US) | 1999-11-02 | — | — | US | disclosed |