Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 14/20 | 0.39 |
| ▸ | HTR2A | P28223 | 13/20 | 0.39 |
| ▸ | DRD3 | P35462 | 13/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489606 | 0.90 | DRD2 (0.45) | GAADRD2 | |
| SCHEMBL8485165 | 0.87 | MGAM (0.41) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8485169 | 0.87 | MGAM (0.41) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8488784 | 0.86 | MGAM (0.41) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8490819 | 0.86 | MGAM (0.48) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8485761 | 0.84 | MGAM (0.47) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8487683 | 0.79 | DRD2 (0.43) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8488457 | 0.78 | MTNR1B (0.54) | DRD2HTR2ADRD3 | |
| SCHEMBL8489458 | 0.76 | MTNR1B (0.46) | DRD2HTR2ADRD3 | |
| SCHEMBL8490024 | 0.76 | DRD2 (0.46) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |