Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522736 | 0.86 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL6732071 | 0.86 | CA2 (0.57) | PTGS2DRD1PTGS1 | |
| SCHEMBL8485289 | 0.81 | PTGS2 (0.70) | PTGS2DRD1PTGS1 | |
| SCHEMBL5502727 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8974242 | 0.78 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL8652283 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6725826 | 0.78 | PTGS2 (0.77) | PTGS2DRD1PTGS1 | |
| SCHEMBL8487062 | 0.77 | DRD1 (0.69) | PTGS2DRD1PTGS1 | |
| SCHEMBL8656962 | 0.77 | SCN9A (0.45) | PTGS2PTGS1 | |
| Hydrogen Sulfide SCHEMBL27744400 | 0.77 | PTGS2 (0.96) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | disclosed |