Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 11/20 | 0.51 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063360 | 0.98 | ALDH1A1 (0.50) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28018780 | 0.80 | KDM4E (0.43) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL10490505 | 0.80 | KDM4E (0.43) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28018743 | 0.80 | KDM4E (0.43) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28018183 | 0.80 | KDM4E (0.43) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28018744 | 0.80 | KDM4E (0.43) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL9244465 | 0.78 | KDM4E (0.41) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL5712077 | 0.77 | ALDH1A1 (0.53) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7386417 | 0.77 | ALDH1A1 (0.46) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL6760699 | 0.75 | ALDH1A1 (0.50) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972929-A | Quinazolinone derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |