SCHEMBL8486263

SCHEMBL8486263

CC(=O)OCC([C]=O)CC[C]=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 1/20 0.34
LMNA P02545 2/20 0.33
HSD17B10 Q99714 1/20 0.33
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3163799 0.69
SCHEMBL10305774 0.69 ALDH1A1 (0.42) USP2ALDH1A1CYP3A4MAPTMEN1
SCHEMBL4667627 0.68
SCHEMBL18643804 0.68
SCHEMBL25457 0.68
SCHEMBL4971091 0.68
SCHEMBL10933947 0.67
SCHEMBL8440671 0.67
SCHEMBL8440668 0.67
SCHEMBL9453839 0.67 SLC22A6 (0.40) MAPTTDP1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6005101-A Glutaryl 7-ACA derivatives and processes for obtaining them ANTIBIOTICOS S.P.A. (IT) 1999-12-21 US disclosed
US-5750682-A Glutaryl 7-ACA derivatives and processes for obtaining them ANTIBIOTICOS S.P.A. (IT) 1998-05-12 US disclosed
EP-0720611-A1 GLUTARYL 7-ACA DERIVATIVES AND PROCESSES FOR OBTAINING THEM ANTIBIOTICOS S.P.A. (IT) 1996-07-10 EP disclosed
WO-1995035020-A2 GLUTARYL 7-ACA DERIVATIVES AND PROCESSES FOR OBTAINING THEM ANTIBIOTICOS S.P.A. (IT) 1995-12-28 WO disclosed