⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428495 | 0.76 | — | — | |
| SCHEMBL20393983 | 0.74 | — | — | |
| SCHEMBL4971091 | 0.74 | — | — | |
| SCHEMBL9453839 | 0.73 | SLC22A6 (0.40) | — | |
| SCHEMBL368682 | 0.72 | — | — | |
| SCHEMBL198521 | 0.69 | — | — | |
| SCHEMBL9465875 | 0.69 | LMNA (0.48) | — | |
| SCHEMBL5133855 | 0.69 | — | — | |
| SCHEMBL4408416 | 0.68 | — | — | |
| SCHEMBL8486263 | 0.68 | USP2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3366 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148264-A1 | HETEROLOGOUS PRODUCTION OF THE C33-C45 POLYKETIDE FRAGMENT OF ANTICANCER APRATOXINS IN A CYANOBACTERIAL HOST | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | WO | claimed |
| CN-118251491-A | CRISPR/Cas related methods and compositions for knockout of C5 | 瑞泽恩制药公司 | 2024-06-25 | — | — | CN | claimed |
| CN-114045270-B | Method for producing ginsenoside Rg1 and special engineering bacterium thereof | 中国科学院天津工业生物技术研究所 | 2024-06-04 | — | — | CN | claimed |
| WO-2024092232-A1 | ANTI-C5 ANTIBODY/C5 IRNA CO-FORMULATIONS AND COMBINATION THERAPIES | REGENERON PHARMACEUTICALS, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| US-11952577-B2 | Yarrowia lipolytica yeast strains expressing an HMG-CoA reductase having increased activity or expression | NUCELIS LLC (US) | 2024-04-09 | — | — | US | claimed |
| CN-117815174-A | Polydopamine coated suspension and application thereof | 复旦大学 | 2024-04-05 | — | — | CN | claimed |
| CN-116875513-B | Pediococcus acidilactici and application thereof in regulating lipid metabolism and protecting liver | 山东宝来利来生物工程股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117363503-A | Engineering bacteria for producing germacrene A/beta-elemene gene and construction method and application thereof | 南京工业大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117248020-A | Application of HMGCL as glioma diagnosis/prognosis marker and treatment target | 山东大学 | 2023-12-19 | — | — | CN | claimed |
| CN-117165462-A | Compartmentalized engineering bacteria for producing bisabolene, and construction method and application thereof | 天津科技大学 | 2023-12-05 | — | — | CN | claimed |
| WO-2001021220-A2 | BIOPROSTHETIC HEART VALVES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-03-29 | — | — | WO | claimed |
| EP-1051977-A1 | RELEASE-SUSTAINING AGENT FOR DRUGS AND SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2000-11-15 | — | — | EP | claimed |
| US-6083985-A | LOVASTATIN, SIMVASTATIN, PRAVASTATIN OR FLUVASTATIN OR DERIVATIVES DECREASES FARNESYL PYROPHOSPHATE IN VIVO; PROTEIN-FARNESYLTRANSFERASE INHIBITOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | claimed |
| EP-0856315-A1 | MEDICINAL COMPOSITION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-08-05 | — | — | EP | claimed |
| EP-0666922-A1 | PLANTS WITH REDUCED SUSCEPTIBILITY TO PLANT-PARASITIC NEMATODES | MOGEN INTERNATIONAL N.V. (NL) | 1995-08-16 | — | — | EP | claimed |
| WO-1994010320-A1 | PLANTS WITH REDUCED SUSCEPTIBILITY TO PLANT-PARASITIC NEMATODES | MOGEN INTERNATIONAL N.V. (NL) | 1994-05-11 | — | — | WO | claimed |
| EP-0572529-A1 | APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING | GILEAD SCIENCES, INC. (US) | 1993-12-08 | — | — | EP | claimed |
| WO-1993010251-A1 | A METHOD FOR OBTAINING PLANTS WITH REDUCED SUSCEPTIBILITY TO PLANT-PARASITIC NEMATODES | MOGEN INTERNATIONAL N.V. (NL) | 1993-05-27 | — | — | WO | claimed |
| WO-1992014843-A1 | APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING | GILEAD SCIENCES, INC. (US) | 1992-09-03 | — | — | WO | claimed |
| EP-0292803-A2 | Process for the production of a HMG-CoA-reductase-like protein | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | claimed |