Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.79 |
| ▸ | CDC25B | P30305 | 4/20 | 0.79 |
| ▸ | CDC25C | P30307 | 4/20 | 0.79 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434535 | 0.81 | MAPT (0.76) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL8486184 | 0.80 | CYP11B1 (0.56) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL8483334 | 0.78 | CDC25A (0.50) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL8524349 | 0.78 | CDC25A (0.59) | CDC25ACDC25BCDC25CDUSP3SMN1; SMN2 | |
| SCHEMBL8636852 | 0.76 | CDC25A (0.57) | CDC25ACDC25BCDC25CDUSP3SMN1; SMN2 | |
| SCHEMBL3604832 | 0.76 | MAPT (0.78) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL8483154 | 0.75 | CDC25A (0.47) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL8486372 | 0.74 | CDC25A (0.72) | CDC25ACDC25BCDC25CDUSP3SMN1; SMN2 | |
| SCHEMBL8525405 | 0.73 | CDC25A (0.51) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL8525097 | 0.73 | CDC25A (0.46) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |