Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 5/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939689 | 0.80 | ALDH1A1 (0.50) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL15391717 | 0.78 | PTGS1 (0.70) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL34464 | 0.78 | PTGS1 (0.70) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL24939685 | 0.77 | ALDH1A1 (0.47) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| Hydrochloric Acid SCHEMBL25414956 | 0.77 | PTGS1 (0.68) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL28981238 | 0.77 | PTGS1 (0.68) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| Hydrazine SCHEMBL20561226 | 0.75 | PTGS1 (0.66) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL20574477 | 0.73 | RGS4 (0.50) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL4400113 | 0.73 | ALDH1A1 (0.58) | PTGS1PTGS2ALDH1A1PKMNPSR1 | |
| SCHEMBL14666849 | 0.73 | ALDH1A1 (0.48) | PTGS1PTGS2ALDH1A1PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912359-A | Dimaleinimido-substituted dihydroxyalkanes which can be used as crosslinking reagents and process for their preparation | FORSCHUNGSZENTRUM JULICH GMBH (DE) | 1999-06-15 | — | — | US | disclosed |