Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | PPARA | Q07869 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486705 | 0.68 | PPARG (0.39) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL8486801 | 0.68 | NPC1 (0.34) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3761024 | 0.62 | KDM4E (0.58) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL9316924 | 0.62 | KDM4E (0.60) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL10447399 | 0.60 | KDM4E (0.57) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL10202989 | 0.59 | KDM4E (0.60) | PPARGPPARALMNAKDM4ERAB9A | |
| SCHEMBL1596084 | 0.59 | KDM4E (0.64) | PPARGPPARALMNAKDM4EMEN1 | |
| SCHEMBL6385812 | 0.59 | PPARA (0.57) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL4029878 | 0.58 | KDM4E (0.52) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL6157744 | 0.58 | FFAR1 (0.53) | PPARGPPARAKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |