Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.39 |
| ▸ | PPARA | Q07869 | 13/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484201 | 0.75 | SIGMAR1 (0.45) | KDM4EMAPT | |
| SCHEMBL8485569 | 0.74 | MAPT (0.39) | PPARGCYP2C9CYP3A4KDM4EMAPT | |
| SCHEMBL8857258 | 0.73 | KDM4E (0.40) | PPARGCYP2C9CYP3A4KDM4EMAPT | |
| SCHEMBL8662202 | 0.73 | PPARG (0.38) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL8857435 | 0.71 | HPGD (0.41) | PPARGCYP2C9CYP3A4KDM4EMAPT | |
| SCHEMBL8669167 | 0.71 | KDM4E (0.46) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL8857701 | 0.71 | KMT2A (0.52) | — | |
| SCHEMBL8486473 | 0.68 | PPARG (0.39) | PPARGPPARALMNAKDM4EMAPT | |
| SCHEMBL8486948 | 0.68 | MAPT (0.44) | PPARGCYP2C9CYP3A4LMNAKDM4E | |
| SCHEMBL6032172 | 0.68 | MAPT (0.53) | PPARGCYP2C9CYP3A4LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |