Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.35 |
| ▸ | PRKCG | P05129 | 2/20 | 0.35 |
| ▸ | PRKCB | P05771 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | PRKCH | P24723 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 2/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427429 | 0.92 | CES2 (0.43) | CES1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL14391542 | 0.78 | — | — | |
| SCHEMBL9320634 | 0.78 | HTT (0.45) | CES1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL21882 | 0.77 | — | — | |
| SCHEMBL4849581 | 0.74 | TSHR (0.43) | CES1CES2THRBGMNNTP53 | |
| SCHEMBL747847 | 0.74 | TSHR (0.43) | CES1CES2THRBGMNNTP53 | |
| Iodide SCHEMBL7869089 | 0.74 | TSHR (0.43) | CES1CES2THRBGMNNTP53 | |
| SCHEMBL10591515 | 0.74 | TSHR (0.43) | CES1CES2THRBGMNNTP53 | |
| SCHEMBL11527395 | 0.74 | TSHR (0.43) | CES1CES2THRBGMNNTP53 | |
| SCHEMBL1406213 | 0.74 | CES2 (0.46) | CES1PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4604951-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | AMIRA THERAPEUTICS, S.L. (ES) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024083861-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | SELABTEC SCIENCES, SLU (ES) | 2024-04-25 | — | — | WO | disclosed |
| CN-109563121-A | 5' S-LNA nucleotides and oligonucleotides | 罗氏创新中心哥本哈根有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-106029666-B | [1,2,4] triazolo [1,5-a ] pyrimidine derivatives as protozoan proteasome inhibitors for the treatment of parasitic diseases such as leishmaniasis | 诺华股份有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-104487485-B | polycarbonate polyol composition and method | 沙特阿美技术公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-106029666-A | [1,2,4] triazolo [1,5-a ] pyrimidine derivatives as protozoan proteasome inhibitors for the treatment of parasitic diseases such as leishmaniasis | 诺华股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-102639492-A | Enantioselective and stereoselective synthesis of beta-amino-alpha-hydroxyamides | SCHERING CORP | 2012-08-15 | — | — | CN | disclosed |
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |
| US-4100200-A | Use of novel ethers as oxydimethylating agents | EASTMAN KODAK COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4025542-A | Novel ethers, their preparation and use as oxydimethylating agents | EASTMAN KODAK COMPANY (US) | 1977-05-24 | — | — | US | disclosed |