Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487175 | 0.89 | MEN1 (0.49) | ALDH1A1PKMMEN1KMT2AHTT | |
| SCHEMBL1876555 | 0.81 | ALDH1A1 (0.71) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8482651 | 0.81 | CYP2D6 (0.54) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1880968 | 0.77 | ALDH1A1 (0.72) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL31014176 | 0.73 | MEN1 (0.76) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL10613191 | 0.72 | MEN1 (0.60) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL411104 | 0.72 | ALDH1A1 (0.79) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL10453840 | 0.71 | ALDH1A1 (0.96) | ALDH1A1PKMLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8794939 | 0.71 | CYP19A1 (0.43) | CYP3A4CYP2C9 | |
| SCHEMBL3370859 | 0.71 | HTR6 (0.48) | ALDH1A1KDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |