Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646783 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EHPGDMTNR1A | |
| SCHEMBL30550497 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EHPGDMTNR1A | |
| SCHEMBL7038840 | 0.73 | NOTUM (0.42) | ALDH1A1HPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL14611924 | 0.72 | KDM4E (0.44) | ALDH1A1MAPTKDM4EHPGDGAA | |
| SCHEMBL7037999 | 0.72 | NUDT1 (0.33) | NUDT1PARP1NOTUM | |
| SCHEMBL25390183 | 0.70 | PARP1 (0.40) | ALDH1A1KDM4EADRB1NUDT1PARP1 | |
| SCHEMBL30471909 | 0.70 | PARP1 (0.40) | ALDH1A1KDM4EADRB1NUDT1PARP1 | |
| SCHEMBL31161318 | 0.69 | EGFR (0.32) | ALDH1A1MAPTKDM4EHPGDMTNR1A | |
| SCHEMBL30504563 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL25403841 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919469-A | Products derived from 2-imino-2,3-dihydro-1H-indoles, processes for their preparation, their use in cosmetics and cosmetic compositions using them | L'OREAL (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0825220-A1 | Products derived from 2-imino-2,3-dihydro-1H-indoles, processes of preparation, use in cosmetics and cosmetic compositions using them | L'OREAL (FR) | 1998-02-25 | — | — | EP | disclosed |