Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490491 | 0.90 | NR1H4 (0.41) | HTTALDH1A1L3MBTL1NR1H4TSHR | |
| SCHEMBL8488004 | 0.88 | HTT (0.45) | HTTALDH1A1THRBTSHRKMT2A | |
| SCHEMBL8491581 | 0.88 | NR1H4 (0.36) | HTTALDH1A1L3MBTL1NR1H4TSHR | |
| SCHEMBL8491675 | 0.87 | NR1H4 (0.36) | HTTALDH1A1L3MBTL1NR1H4KMT2A | |
| SCHEMBL8492713 | 0.87 | NR1H2 (0.37) | HTTALDH1A1L3MBTL1NR1H4MLYCD | |
| SCHEMBL8488638 | 0.86 | HTT (0.44) | HTTALDH1A1THRBTSHRKMT2A | |
| SCHEMBL8491826 | 0.86 | HTT (0.44) | HTTALDH1A1THRBTSHRKMT2A | |
| SCHEMBL8525752 | 0.86 | NR1H4 (0.41) | HTTALDH1A1NR1H4NPSR1MLYCD | |
| SCHEMBL9116715 | 0.85 | HTT (0.41) | HTTALDH1A1THRBTSHRKMT2A | |
| SCHEMBL8488086 | 0.85 | MLYCD (0.40) | HTTALDH1A1THRBMLYCDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |