Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 10/20 | 0.42 |
| ▸ | FPR1 | P21462 | 9/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738285 | 0.83 | HRH3 (0.37) | FPR2FPR1DRD2 | |
| SCHEMBL7744111 | 0.83 | HRH3 (0.37) | FPR2FPR1DRD2 | |
| SCHEMBL7746101 | 0.81 | CYP19A1 (0.43) | FPR2FPR1DRD2 | |
| Trifluoroacetic Acid SCHEMBL7743550 | 0.81 | FPR1 (0.37) | FPR2FPR1PRKAA2 | |
| SCHEMBL7746078 | 0.81 | KCNJ1 (0.39) | FPR2FPR1ALDH1A1 | |
| SCHEMBL7738184 | 0.80 | CYP19A1 (0.41) | FPR2FPR1 | |
| SCHEMBL7743502 | 0.80 | MAPT (0.43) | DRD2KDM4EALDH1A1 | |
| SCHEMBL7744150 | 0.79 | HRH3 (0.37) | DRD2 | |
| SCHEMBL7744222 | 0.79 | CYP11B1 (0.37) | — | |
| SCHEMBL7190259 | 0.78 | FNTA (0.42) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977134-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | disclosed |