Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491997 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6445542 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL6438225 | 0.79 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL4959110 | 0.77 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL7482340 | 0.77 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7539198 | 0.76 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6620090 | 0.76 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5078441 | 0.75 | PTGS2 (0.53) | PTGS2PTGS1MAPK14 | |
| SCHEMBL6180483 | 0.75 | PTGS2 (0.53) | PTGS2PTGS1MAPK14 | |
| SCHEMBL7489424 | 0.74 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999025695-A1 | 5-ARYLPYRAZOLE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-27 | — | — | WO | disclosed |