SCHEMBL8487166

SCHEMBL8487166

COc1cc(SCl)cc(SCl)c1.Sc1cc(Cl)cc(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.36
ALDH1A1 P00352 1/20 0.34
IDO1 P14902 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1713073 0.82 ALDH1A1 (0.50) AHRALDH1A1IDO1
SCHEMBL3646752 0.78 ALDH1A1 (0.46) AHRALDH1A1
SCHEMBL811578 0.71 ALDH1A1 (0.59) AHRALDH1A1
SCHEMBL3786357 0.69 ALDH1A1 (0.42) ALDH1A1
SCHEMBL4123128 0.68 TSHR (0.53) AHRALDH1A1IDO1
SCHEMBL441794 0.68
SCHEMBL16562812 0.67 CYP1A1 (0.43) AHRALDH1A1IDO1
SCHEMBL21263 0.66 ALDH1A1 (0.69) AHRALDH1A1
SCHEMBL388334 0.66 ALDH1A1 (0.69) AHRALDH1A1
SCHEMBL8487167 0.66 TSHR (0.38) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed
US-5741933-A HYDROLYSIS; OXIDATION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-21 US disclosed