Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275952 | 0.87 | — | — | |
| SCHEMBL487511 | 0.87 | — | — | |
| SCHEMBL27464590 | 0.85 | PTGS2 (0.55) | PTGS2NR1H2ALDH1A1RAB9AMEN1 | |
| SCHEMBL17365268 | 0.80 | ALDH1A1 (0.41) | PTGS2NR1H2ALDH1A1LMNAHPGD | |
| SCHEMBL21186097 | 0.80 | ALDH1A1 (0.41) | PTGS2ALDH1A1NOS3NOS1PLK1 | |
| SCHEMBL11171221 | 0.80 | NR1H2 (0.50) | NR1H2ALDH1A1RAB9AMEN1LMNA | |
| SCHEMBL15932963 | 0.80 | NR1H2 (0.74) | NR1H2ALDH1A1RAB9AMEN1LMNA | |
| SCHEMBL10530044 | 0.80 | PTGS2 (0.62) | PTGS2NR1H2ALDH1A1RAB9AMEN1 | |
| SCHEMBL27461078 | 0.80 | NR1H2 (0.74) | PTGS2NR1H2ALDH1A1RAB9AMEN1 | |
| SCHEMBL6826375 | 0.79 | PLK1 (0.45) | ALDH1A1RAB9AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932731-A | HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| US-5741933-A | HYDROLYSIS; OXIDATION | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |