SCHEMBL8487255

SCHEMBL8487255

CCCCCCCCCCCCC(O)COc1ccccc1-c1[c]cccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ADRB2 P07550 4/20 0.38
ADRB1 P08588 3/20 0.38
PPARG P37231 2/20 0.37
ALOX15 P16050 2/20 0.36
LMNA P02545 2/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 2/20 0.36
KDM4E B2RXH2 1/20 0.36
AGTR1 P30556 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3867574 0.82 CYP1A2 (0.47) KMT2AMEN1LMNACYP1A2KDM4E
SCHEMBL3688430 0.81 S1PR1 (0.45) LMNATP53TSHRMAPK1SMN1; SMN2
SCHEMBL7249592 0.80 KMT2A (0.42) KMT2AMEN1ADRB2ADRB1PPARG
SCHEMBL4455828 0.79 KMT2A (0.41) KMT2AMEN1ADRB2ADRB1PPARG
SCHEMBL8487258 0.78 MEN1 (0.39) KMT2AMEN1ADRB2ADRB1PPARG
SCHEMBL30051714 0.77 ADRB2 (0.46) KMT2AMEN1ADRB2ADRB1PPARG
SCHEMBL2459089 0.77 ADRB2 (0.46) KMT2AMEN1ADRB2ADRB1PPARG
SCHEMBL18038533 0.76 HTR1A (0.49) KMT2AMEN1PPARGALOX15LMNA
SCHEMBL4623399 0.76 ADRB2 (0.38) ADRB2ADRB1KDM4E
SCHEMBL27838229 0.75 ADRB2 (0.59) KMT2AMEN1ADRB2ADRB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939698-A1 THERMAL LITHOGRAPHIC PRINTING PLATES Kodak Polychrome Graphics LLC (US) 1999-09-08 EP disclosed
WO-1999011458-A1 THERMAL LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 1999-03-11 WO disclosed