Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487259 | 0.85 | MTNR1A (0.36) | SLC6A4MTNR1AMTNR1BCYP1A1CYP1A2 | |
| SCHEMBL27463661 | 0.85 | MTNR1A (0.36) | SLC6A4MTNR1AMTNR1BCYP1A1CYP1A2 | |
| Methyl Alcohol SCHEMBL27547344 | 0.83 | MTNR1A (0.37) | SLC6A4MTNR1AMTNR1BCYP1A1CYP1A2 | |
| Methylamine SCHEMBL27481947 | 0.83 | MTNR1A (0.34) | SLC6A4MTNR1AMTNR1BCYP1A1CYP1A2 | |
| SCHEMBL6682738 | 0.81 | HTR2C (0.54) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL6682734 | 0.81 | HTR2C (0.54) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL6677157 | 0.80 | MTNR1A (0.35) | SLC6A4MTNR1AMTNR1BCYP1A1CYP1A2 | |
| SCHEMBL6677159 | 0.80 | MTNR1A (0.35) | SLC6A4MTNR1AMTNR1BCYP1A1CYP1A2 | |
| SCHEMBL24458750 | 0.79 | PDK2 (0.36) | SLC6A4CYP1A1CYP1A2CYP1B1HTR2C | |
| Methylamine SCHEMBL27481195 | 0.77 | PDK2 (0.35) | SLC6A4CYP1A1CYP1A2CYP1B1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |