Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487280 | 1.00 | GRIN1 (0.35) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL8489000 | 0.85 | MEN1 (0.34) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL8488999 | 0.85 | MEN1 (0.34) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL8488510 | 0.85 | GRIN1 (0.49) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL7467566 | 0.85 | GRIN1 (0.39) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL7470510 | 0.84 | RAB9A (0.46) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL8489890 | 0.83 | GRIN1 (0.37) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL7470542 | 0.81 | GRIN1 (0.39) | GRIN1MEN1PKMKMT2A | |
| SCHEMBL8650855 | 0.81 | GRIN1 (0.42) | GRIN1MEN1PKMKMT2ARAB9A | |
| SCHEMBL8490082 | 0.81 | GRIN1 (0.37) | GRIN1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863917-A | ANXIOLYTIC AGENT, ANTICONVULSANTS, ANALGESICS AND NEUROPROTECTIVES. | PFIZER, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1997031902-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-04 | — | — | WO | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |