Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487302 | 0.92 | MEN1 (0.43) | MEN1KMT2ACA2AOX1 | |
| SCHEMBL8486547 | 0.90 | MEN1 (0.42) | MEN1KMT2ACA2AOX1 | |
| SCHEMBL27537966 | 0.89 | MEN1 (0.41) | MEN1KMT2ACA2AOX1 | |
| SCHEMBL8484070 | 0.88 | AOX1 (0.51) | MEN1KMT2ACA2AOX1ACHE | |
| SCHEMBL8483591 | 0.81 | MEN1 (0.42) | MEN1KMT2ACA2AOX1TSHR | |
| SCHEMBL8412588 | 0.80 | MEN1 (0.49) | MEN1KMT2AAOX1 | |
| SCHEMBL6999357 | 0.78 | MEN1 (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8487370 | 0.78 | CETP (0.49) | MEN1KMT2A | |
| SCHEMBL5483767 | 0.77 | MEN1 (0.67) | MEN1KMT2ACA2AOX1ACHE | |
| SCHEMBL7916451 | 0.76 | AOX1 (0.58) | MEN1KMT2AAOX1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090621-C | Process for preparing quinazolin-4-one derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| US-5922866-A | REACTING A TRIALKYLSILYL HALIDE WITH A 1,2-AMIDE SUBSTITUTED BENZENE DERIVATIVE IN THE PRESENCE OF A BASE; USE AS PHARMACEUTICALS OR INTERMEDIATES FOR SYNTHESIS THEREOF, SUCH AS ANTIDIABETIC DRUGS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |
| CN-1193967-A | Process for producing quinazoline-4-one derivatives | OTSUKA PHARMA CO LTD (US) | 1998-09-23 | — | — | CN | disclosed |