Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490392 | 0.82 | CHRM1 (0.62) | MAPK1CHRM1L3MBTL1TP53TDP1 | |
| SCHEMBL12967015 | 0.81 | MAPK1 (0.70) | MAPK1CHRM1L3MBTL1TP53TDP1 | |
| Hydrochloric Acid SCHEMBL8489849 | 0.80 | MAPK1 (0.47) | MAPK1CHRM1L3MBTL1MEN1KMT2A | |
| SCHEMBL6306521 | 0.79 | TSHR (0.44) | MAPK1L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4516164 | 0.77 | L3MBTL1 (0.52) | MAPK1CHRM1L3MBTL1TP53TDP1 | |
| SCHEMBL4516367 | 0.76 | TSHR (0.49) | L3MBTL1MEN1KMT2ATDP1GAA | |
| SCHEMBL21047822 | 0.75 | L3MBTL3 (0.37) | MAPK1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL21047677 | 0.75 | MAPK1 (0.40) | MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL13243426 | 0.74 | CHRM1 (0.52) | MAPK1CHRM1L3MBTL1MEN1KMT2A | |
| SCHEMBL8490717 | 0.74 | CHRM1 (0.56) | MAPK1CHRM1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032445-A1 | OXIMINO-PIPERIDINE, -PYRROLIDINE AND -AZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MUSCARINIC RECEPTOR (ANT-)AGONISTS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |