Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647579 | 0.85 | GRIK1 (0.58) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL547637 | 0.85 | GRIK1 (0.58) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL7298560 | 0.81 | PPM1D (0.53) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL2018862 | 0.81 | GRIK1 (0.51) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL2517985 | 0.79 | GRIK1 (0.50) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL8486506 | 0.78 | GRIK1 (0.46) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL18043819 | 0.76 | CYP2C9 (0.50) | GRIK1FOLH1ALDH1A1CYP2C9HTT | |
| SCHEMBL15058447 | 0.76 | SCN1A (0.50) | GRIK1ALDH1A1CYP2C9 | |
| SCHEMBL2289368 | 0.75 | FOLH1 (0.49) | GRIK1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL10514159 | 0.74 | ALDH1A1 (0.48) | GRIK1ALDH1A1CYP2C9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912356-A | HERPES VIRUS | GLAXO WELLCOME INC. (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0630368-B1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | WELLCOME FOUND (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5534535-A | ANTIVIRAL ANALOGS WITH SUBSTITUTED BENZIMIDAZOLE BASE | BURROUGHS WELLCOME CO. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5399580-A | Viricides for hepatitis B | BURROUGHS WELLCOME CO. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0630368-A1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018009-A1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |