Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482882 | 0.99 | MAOB (0.39) | MAOBMAOAPRKCQPRKCDNPC1 | |
| SCHEMBL8808908 | 0.87 | MAOB (0.39) | MAOBMAOAPRKCQPRKCDMYC | |
| SCHEMBL8806612 | 0.86 | MAOB (0.38) | MAOBMAOAPRKCQPRKCDMYC | |
| SCHEMBL8485794 | 0.84 | ABL1 (0.42) | NPC1RAB9AMEN1KMT2AMYC | |
| SCHEMBL2311 | 0.82 | ITGB1 (0.43) | NPC1RAB9AMEN1KMT2AMYC | |
| SCHEMBL8483018 | 0.82 | KDM4E (0.37) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9079126 | 0.82 | S1PR1 (0.35) | PRKCQPRKCDNPC1RAB9AMEN1 | |
| SCHEMBL2563 | 0.81 | ITGB1 (0.42) | NPC1RAB9AMEN1KMT2AMYC | |
| SCHEMBL8487248 | 0.81 | LTB4R2 (0.34) | MAOBMAOAPRKCQPRKCDNPC1 | |
| SCHEMBL8484799 | 0.80 | LTB4R2 (0.34) | MAOBMAOAPRKCQPRKCDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955487-A | TREATING HIGH BLOOD PRESSURE, CARDIAC INSUFFICIENCY, GLAUCOMA | CIBA-GEIGY CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |