Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806612 | 0.99 | MAOB (0.38) | MAOBMAOAPRKCQPRKCDCD274 | |
| SCHEMBL8487461 | 0.87 | MAOB (0.40) | MAOBMAOAPRKCQPRKCDMYC | |
| SCHEMBL8482882 | 0.86 | MAOB (0.39) | MAOBMAOAPRKCQPRKCDMYC | |
| SCHEMBL8813977 | 0.85 | ABL1 (0.41) | CD274MYCWDR5KDM4EALDH1A1 | |
| SCHEMBL7280200 | 0.83 | ACHE (0.44) | CD274MYCWDR5KDM4EALDH1A1 | |
| SCHEMBL8808945 | 0.82 | S1PR1 (0.34) | PRKCQPRKCDCD274MYCWDR5 | |
| SCHEMBL8808660 | 0.82 | KCNH2 (0.36) | CD274KDM4EALDH1A1HSD17B10HRH3 | |
| SCHEMBL7278807 | 0.82 | ACHE (0.43) | CD274MYCWDR5KDM4EALDH1A1 | |
| SCHEMBL8811173 | 0.81 | S1PR1 (0.34) | MAOBMAOAPRKCQPRKCDMYC | |
| SCHEMBL8808994 | 0.81 | S1PR1 (0.34) | MAOBMAOAPRKCQPRKCDMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528762-B1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| EP-0528762-A1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA-GEIGY AG (CH) | 1993-02-24 | — | — | EP | disclosed |