⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336772 | 1.00 | — | — | |
| Diphenylsulfane SCHEMBL9746866 | 0.87 | KDM4E (0.45) | — | |
| SCHEMBL8487569 | 0.87 | MAPT (0.40) | — | |
| SCHEMBL22195508 | 0.80 | IDO1 (0.47) | — | |
| SCHEMBL7596666 | 0.80 | HSD11B1 (0.42) | — | |
| SCHEMBL28259998 | 0.80 | HPGD (0.42) | — | |
| SCHEMBL25971182 | 0.79 | FBP1 (0.44) | — | |
| SCHEMBL1146294 | 0.79 | MAPT (0.53) | — | |
| SCHEMBL812717 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL4030686 | 0.77 | MAPT (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112210278-A | Polyurea spraying elastomer for pipeline corrosion prevention | 常州市大使涂料有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-109135526-A | A kind of synthesis technology of epoxidized soybean oil modified polyaspartic acid ester polyurea copolymers | 成都上泰科技有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108623561-A | A method of preparing piperazine Nino acid compound | 中国海洋大学 | 2018-10-09 | — | — | CN | claimed |
| CN-108623581-A | A method of preparing piperazine Nino peace compound | 中国海洋大学 | 2018-10-09 | — | — | CN | claimed |
| CN-103757932-B | Flat duck dipping solution formula and preparation technology thereof | Wuhu S.H.Z Industrial Fabric Co., Ltd. (CN) | 2015-12-02 | — | — | CN | claimed |
| US-7220770-B2 | Heterocyclo-substituted imidazoles for the treatment of inflammation | KHANNA ISH K | 2007-05-22 | — | — | US | claimed |
| US-20050256120-A1 | Heterocyclo-substituted imidazoles for the treatment of inflammation | KHANNA ISH K | 2005-11-17 | — | — | US | claimed |
| EP-1171417-B1 | METHODS FOR PREPARING 3-ARYLOXY-3-ARYLPROPYLAMINES AND INTERMEDIATES THEREOF | LILLY CO ELI (US) | 2005-11-09 | — | — | EP | claimed |
| US-20050096368-A1 | Heterocyclo-substituted imidazoles for the treatment of inflammation | G.D. SEARLE & CO. | 2005-05-05 | — | — | US | claimed |
| US-6613789-B2 | Especially for treating arthritis, pain and fever | G. D. SEARLE & CO. | 2003-09-02 | — | — | US | claimed |
| US-20030036557-A1 | Heterocyclo-substituted imidazoles for the treatment of inflammation | G.D. SEARLE & CO. | 2003-02-20 | — | — | US | claimed |
| EP-0772600-B1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2002-09-18 | — | — | EP | claimed |
| EP-1171417-A1 | METHODS FOR PREPARING 3-ARYLOXY-3-ARYLPROPYLAMINES AND INTERMEDIATES THEREOF | ELI LILLY AND COMPANY (US) | 2002-01-16 | — | — | EP | claimed |
| WO-2000061540-A1 | METHODS FOR PREPARING 3-ARYLOXY-3-ARYLPROPYLAMINES AND INTERMEDIATES THEREOF | ELI LILLY AND COMPANY (US) | 2000-10-19 | — | — | WO | claimed |
| EP-0880504-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-12-02 | — | — | EP | claimed |
| WO-1997027181-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-07-31 | — | — | WO | claimed |
| EP-0772600-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | claimed |
| US-5616601-A | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation | GD SEARLE & CO (US) | 1997-04-01 | — | — | US | claimed |
| WO-1996003388-A1 | 1,2-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |