Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485482 | 0.90 | NQO1 (0.41) | TOP2ATOP2BALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8482943 | 0.87 | TOP2A (0.42) | TOP2ATOP2BALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10810013 | 0.86 | TOP2A (0.48) | TOP2ATOP2BALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8487902 | 0.85 | MAPT (0.35) | ALDH1A1MAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8486373 | 0.84 | KMT2A (0.33) | ALDH1A1MAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8485606 | 0.84 | TOP2A (0.42) | TOP2ATOP2BALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8487417 | 0.82 | TOP2A (0.44) | TOP2ATOP2BL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL10813550 | 0.81 | TOP2A (0.42) | TOP2ATOP2BALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8486344 | 0.80 | TOP2A (0.40) | TOP2AALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL10925940 | 0.79 | TOP2A (0.65) | TOP2ATOP2BMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935969-A | Pyrido-thiopyrandoinazoles with antitumor activity | UNIVERSITY OF VERMONT (US) | 1999-08-10 | — | — | US | disclosed |