Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487700 | 0.90 | PDE4A (0.47) | KMT2AKDM4EMEN1MITFALDH1A1 | |
| SCHEMBL8491746 | 0.88 | ALDH1A1 (0.40) | KMT2AKDM4EMEN1MITFALDH1A1 | |
| SCHEMBL8525770 | 0.86 | HCRTR2 (0.41) | KMT2AMEN1ALDH1A1HTTHCRTR2 | |
| SCHEMBL8491830 | 0.86 | NR1H4 (0.40) | KMT2AKDM4EMEN1MITFALDH1A1 | |
| SCHEMBL8490079 | 0.85 | KDM4E (0.38) | KMT2AKDM4EMEN1MITFALDH1A1 | |
| SCHEMBL8490872 | 0.85 | KDM4E (0.33) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8524135 | 0.85 | SMN1; SMN2 (0.39) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8488620 | 0.84 | NPC1 (0.35) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8492214 | 0.84 | KDM4E (0.37) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8492485 | 0.82 | LMNA (0.34) | KMT2AKDM4EMEN1MITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |