Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485197 | 0.94 | KMT2A (0.78) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL8484513 | 0.91 | ADORA3 (0.61) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL27416186 | 0.84 | KMT2A (0.64) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL2754553 | 0.82 | KMT2A (1.00) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL8769970 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL8619064 | 0.82 | MEN1 (0.64) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL16376447 | 0.82 | MEN1 (0.77) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL20220277 | 0.82 | MEN1 (0.77) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL20413823 | 0.82 | MEN1 (0.77) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL12655454 | 0.82 | MEN1 (0.77) | ALDH1A1KMT2AKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922743-A | USEFUL FOR AMELIORATION OF NERVE DISORDERS DUE TO NEURONAL DEGENERATION, SUCH AS INDUCED BY DRUGS OR ALCOHOL, INFLAMMATORY DISORDERS, DIABETES, ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, HUNTINGTON'S CHOREA, AND OTHERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0795545-A1 | PYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1997-09-17 | — | — | EP | disclosed |