Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485433 | 0.81 | KDM4E (0.60) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL7374466 | 0.80 | KDM4E (0.52) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL8487156 | 0.73 | POLB (0.44) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL8541313 | 0.72 | CYP3A4 (0.46) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7372501 | 0.72 | KDM4E (0.54) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL8029944 | 0.70 | SIGMAR1 (0.53) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL16130555 | 0.70 | KDM4E (0.70) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| SCHEMBL8144593 | 0.69 | KDM4E (0.66) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL27781452 | 0.69 | KDM4E (0.69) | KDM4ELMNAALDH1A1HTT | |
| SCHEMBL8029589 | 0.69 | TSHR (0.61) | KDM4ELMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |