Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370824 | 0.92 | SIGMAR1 (0.47) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8488018 | 0.73 | POLB (0.52) | POLBALDH1A1MEN1KMT2APKM | |
| SCHEMBL7377176 | 0.72 | SIGMAR1 (0.44) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8485433 | 0.71 | KDM4E (0.60) | POLBALDH1A1MEN1KMT2APKM | |
| SCHEMBL7374466 | 0.70 | KDM4E (0.52) | POLBALDH1A1MEN1KMT2APKM | |
| SCHEMBL8487208 | 0.67 | MEN1 (0.47) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8491628 | 0.67 | CYP2D6 (0.48) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL7373091 | 0.66 | SIGMAR1 (0.54) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL24199876 | 0.64 | SIGMAR1 (0.68) | POLBALDH1A1PKMKDM4ELMNA | |
| SCHEMBL8487205 | 0.64 | HSD17B10 (0.57) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |