Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.42 |
| ▸ | RXRG | P48443 | 10/20 | 0.41 |
| ▸ | RXRB | P28702 | 9/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049173 | 1.00 | RXRA (0.42) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL9049181 | 1.00 | RXRA (0.42) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL9049102 | 0.84 | RARB (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8487114 | 0.84 | RARB (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL9049113 | 0.84 | RARB (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8189844 | 0.83 | RXRA (0.62) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8189841 | 0.83 | RXRA (0.62) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6877487 | 0.80 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6874278 | 0.78 | RXRA (0.47) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6870432 | 0.77 | RXRA (0.46) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968908-A | Restricted 9-cis retinoids | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |