Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.50 |
| ▸ | RARG | P13631 | 12/20 | 0.50 |
| ▸ | RXRA | P19793 | 6/20 | 0.50 |
| ▸ | RARA | P10276 | 12/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487114 | 1.00 | RARB (0.50) | RARBRARGRXRARARAPTGER1 | |
| SCHEMBL9049113 | 1.00 | RARB (0.50) | RARBRARGRXRARARAPTGER1 | |
| SCHEMBL8488116 | 0.84 | RXRA (0.42) | RARBRARGRXRARARARXRG | |
| SCHEMBL9049181 | 0.84 | RXRA (0.42) | RARBRARGRXRARARARXRG | |
| SCHEMBL9049173 | 0.84 | RXRA (0.42) | RARBRARGRXRARARARXRG | |
| SCHEMBL4882500 | 0.83 | RXRA (0.62) | RARBRARGRXRARARARXRG | |
| SCHEMBL4882513 | 0.83 | RXRA (0.62) | RARBRARGRXRARARARXRG | |
| SCHEMBL7567586 | 0.80 | KDM4E (0.47) | RARBRARGRXRARARARXRG | |
| SCHEMBL7565108 | 0.80 | KDM4E (0.47) | RARBRARGRXRARARARXRG | |
| SCHEMBL6880799 | 0.77 | RARB (0.51) | RARBRARGRXRARARAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718285-A2 | Restricted 9-cis-retinoids | American Cyanamid Company (US) | 1996-06-26 | — | — | EP | disclosed |