Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 14/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 14/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 14/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.57 |
| ▸ | RAF1 | P04049 | 2/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.46 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.46 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.46 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.46 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.46 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.46 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.46 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.46 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695632 | 0.81 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL8488141 | 0.79 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7215450 | 0.78 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7215445 | 0.78 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL14561106 | 0.78 | MAPK13 (0.60) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| Hydrochloric Acid SCHEMBL8489047 | 0.78 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5818671 | 0.77 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL14561108 | 0.76 | MAPK13 (0.60) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7221081 | 0.76 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7217284 | 0.76 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859041-A | Substituted imidazoles having cytokine inhibitory activity | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |