Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.47 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489824 | 0.90 | MAPK14 (0.55) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL8487974 | 0.89 | CPT2 (0.43) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL8489467 | 0.88 | CSNK1A1 (0.48) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL8487132 | 0.87 | CSNK1A1 (0.47) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL6170576 | 0.87 | MAPK14 (0.49) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL8603520 | 0.86 | MAPK14 (0.53) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL8488549 | 0.86 | MAPK14 (0.62) | CSNK1A1CSNK1DRPS6KA3MAPK14MAPK13 | |
| SCHEMBL8488352 | 0.85 | BTK (0.44) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL8485395 | 0.85 | BTK (0.44) | HCRTR1HCRTR2CPT2CPT1ACPT1B | |
| SCHEMBL8485629 | 0.85 | MAPK14 (0.64) | HCRTR1HCRTR2CPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859041-A | Substituted imidazoles having cytokine inhibitory activity | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |