Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 4/20 | 0.48 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.41 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174028 | 0.91 | TRPC3 (0.41) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL6172458 | 0.89 | MAPK13 (0.64) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL14174029 | 0.89 | MAPK14 (0.51) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL6174413 | 0.89 | CSNK1A1 (0.65) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL6170828 | 0.88 | MAPK13 (0.49) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL7455444 | 0.88 | TRPV4 (0.40) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL6222724 | 0.88 | CSNK1A1 (0.55) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL8488208 | 0.87 | HCRTR1 (0.47) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL6172475 | 0.87 | CSNK1A1 (0.54) | MAPK14MAPK13MAPK9MAPK12MAPK11 | |
| SCHEMBL7529385 | 0.86 | MAPK13 (0.48) | MAPK14MAPK13MAPK9MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139596-A1 | Modulators of Hcv Replication | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-06-12 | — | — | US | disclosed |
| EP-0906307-B1 | SUBSTITUTED IMIDAZOLES HAVING CYTOKINE INHIBITORY ACTIVITY | MERCK & CO INC (US) | 2005-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139596-A1 | Modulators of Hcv Replication | EIF2AK2, MAVS, IRF3 | MAPK14 1644/4885MAPK13 2427/4885MAPK9 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.