Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035030 | 0.81 | MAOA (0.52) | MAOAMAOBCYP19A1TAAR1SIGMAR1 | |
| SCHEMBL29432882 | 0.79 | TAAR1 (0.57) | TAAR1SIGMAR1MEN1KMT2A | |
| SCHEMBL3061311 | 0.79 | TAAR1 (0.52) | TAAR1MEN1KMT2AGRM2GRM3 | |
| SCHEMBL1499422 | 0.79 | TAAR1 (0.57) | TAAR1SIGMAR1MEN1KMT2A | |
| SCHEMBL22170215 | 0.78 | MAOB (0.57) | MAOAMAOBCYP19A1SIGMAR1GRM2 | |
| SCHEMBL24137898 | 0.77 | MEN1 (0.62) | TAAR1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL2077308 | 0.77 | MEN1 (0.62) | TAAR1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL52143 | 0.77 | MEN1 (0.62) | TAAR1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL2154372 | 0.76 | MAOB (0.86) | MAOAMAOBCYP19A1SIGMAR1PARP1 | |
| SCHEMBL29436994 | 0.76 | MAOB (0.86) | MAOAMAOBCYP19A1SIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936104-A | Process for producing 1,2-epoxy-3-amino-4-phenylbutane derivatives | KANEKA CORPORATION (JP) | 1999-08-10 | — | — | US | claimed |