Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.53 |
| ▸ | MAP1LC3A | Q9H492 | 4/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.53 |
| ▸ | NQO1 | P15559 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277138 | 0.99 | MAP1LC3B (0.53) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL6277201 | 0.99 | MAP1LC3B (0.53) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL8488462 | 0.99 | MAP1LC3B (0.53) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL8489872 | 0.99 | MAP1LC3B (0.53) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL6276622 | 0.96 | MAP1LC3B (0.57) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL8492040 | 0.92 | NQO1 (0.55) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL8489977 | 0.90 | HSD17B3 (0.53) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL8490526 | 0.88 | HSD17B3 (0.52) | MAP1LC3BMAP1LC3AHSD17B3NQO1ALDH1A1 | |
| SCHEMBL6272846 | 0.88 | ALOX15 (0.51) | MAP1LC3BMAP1LC3AHSD17B3PGAM1 | |
| SCHEMBL8494936 | 0.88 | ALOX15 (0.51) | MAP1LC3BMAP1LC3AHSD17B3PGAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8259556-A | — | — | None | — | — | JP | disclosed |
| CN-1101678-C | Benzopyran derivative and therapeutic agent for heart disease containing the same as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2003-02-19 | — | — | CN | disclosed |
| US-5981495-A | TREATING HEART DISEASE BY ADMINISTERING TO THE HEART PATIENT A BENOPYRAN DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-11-09 | — | — | US | disclosed |
| CN-1164999-A | Benzopyran derivative and therapeutic agent for heart disease containing the same as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 1997-11-19 | — | — | CN | disclosed |
| EP-0796854-A1 | Benzopyran derivative and use of said benzopyran derivative for treating heart disease | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-09-24 | — | — | EP | disclosed |
| JP-H08259556-A | 4,7-HYDROXYBENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEM INC | 1996-10-08 | — | — | JP | disclosed |