Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537368 | 0.84 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL8489642 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL441707 | 0.78 | HAVCR2 (0.63) | ALDH1A1KDM4EHAVCR2PDE10ASMN1; SMN2 | |
| SCHEMBL317836 | 0.78 | KMT2A (1.00) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL11722245 | 0.76 | TDP1 (0.62) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL6537483 | 0.75 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL6537643 | 0.75 | MEN1 (0.59) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL2098010 | 0.74 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL6985429 | 0.74 | KMT2A (0.54) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL441422 | 0.73 | HAVCR2 (0.46) | HAVCR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |