Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441707 | 0.83 | HAVCR2 (0.63) | HAVCR2PARP1NR4A2ACHESMN1; SMN2 | |
| SCHEMBL442157 | 0.79 | HAVCR2 (0.36) | HAVCR2 | |
| SCHEMBL435823 | 0.79 | PARP1 (0.41) | HAVCR2PARP1GRM5SMN1; SMN2 | |
| SCHEMBL442075 | 0.79 | HAVCR2 (0.46) | HAVCR2PARP1NR4A2ACHESMN1; SMN2 | |
| SCHEMBL437767 | 0.79 | HAVCR2 (0.46) | HAVCR2NR4A2ACHE | |
| SCHEMBL18635471 | 0.79 | PARP1 (0.41) | HAVCR2PARP1GRM5PIK3R2 | |
| SCHEMBL437574 | 0.78 | PARP1 (0.45) | HAVCR2PARP1NR4A2CDK2 | |
| SCHEMBL23126271 | 0.75 | PARP1 (0.41) | HAVCR2PARP1GRM5SMN1; SMN2 | |
| SCHEMBL440416 | 0.75 | CDK8 (0.33) | HAVCR2CDK9 | |
| SCHEMBL16132381 | 0.75 | GRM5 (0.40) | PARP1GRM5PTGESJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |