Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545783 | 0.96 | DRD4 (0.48) | CHEK1DRD4KDM4EMEN1MAPT | |
| SCHEMBL3052957 | 0.88 | DRD4 (0.49) | CHEK1DRD4MAPTKMT2ALMNA | |
| SCHEMBL3052249 | 0.87 | SMN1; SMN2 (0.55) | CHEK1DRD4MAPTKMT2ALMNA | |
| SCHEMBL3185266 | 0.86 | DRD4 (0.57) | CHEK1DRD4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30121999 | 0.84 | MAPT (0.51) | DRD4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL3701823 | 0.84 | MAPT (0.51) | DRD4KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10552656 | 0.83 | ALDH1A1 (0.44) | CHEK1DRD4MEN1MAPTKMT2A | |
| SCHEMBL15260163 | 0.83 | DRD4 (0.47) | DRD4KDM4EMAPTKMT2ALMNA | |
| SCHEMBL1136179 | 0.83 | TSHR (0.44) | CHEK1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10547312 | 0.83 | TDP1 (0.48) | DRD4KDM4EMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999065891-A1 | NOVEL 2,4-DIAMINOPHENOL DERIVATIVES AND THE USE THEREOF | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1999-12-23 | — | — | WO | disclosed |