Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.56 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.56 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.56 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.56 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.56 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.56 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.56 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.56 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.56 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.56 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488507 | 1.00 | ALOX15 (0.58) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8490417 | 0.95 | ALOX15 (0.62) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8489840 | 0.91 | TDP1 (0.55) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8489846 | 0.91 | TDP1 (0.55) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6277116 | 0.90 | ALOX15 (0.54) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6277123 | 0.90 | ALOX15 (0.54) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6277118 | 0.90 | MAOB (0.51) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6277111 | 0.90 | MAOB (0.51) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8494210 | 0.90 | ALOX15 (0.52) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8494200 | 0.90 | ALOX15 (0.52) | ALOX15TDP1CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981495-A | TREATING HEART DISEASE BY ADMINISTERING TO THE HEART PATIENT A BENOPYRAN DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0796854-A1 | Benzopyran derivative and use of said benzopyran derivative for treating heart disease | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-09-24 | — | — | EP | disclosed |