SCHEMBL8488573

SCHEMBL8488573

CCCCN(C1CN(CC(C)O)CCN(CC(=O)[O-])CCN(CC(=O)[O-])CCN1CC(=O)[O-])S(C)(=O)=O.[Gd+3]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8486397 0.96
SCHEMBL8489660 0.96
SCHEMBL8489937 0.88 SIGMAR1 (0.33) SIGMAR1
SCHEMBL8488054 0.87
SCHEMBL8491771 0.84 SIGMAR1 (0.35) SIGMAR1
SCHEMBL8490617 0.84 S1PR1 (0.36) SIGMAR1
SCHEMBL8485655 0.84 S1PR1 (0.36) SIGMAR1
SCHEMBL8488416 0.83 ALDH1A1 (0.39) ALDH1A1
SCHEMBL8484817 0.81 MAPK1 (0.38) ALDH1A1
SCHEMBL8487218 0.81 MEN1 (0.33) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919431-A 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-06 US disclosed