SCHEMBL8779795

SCHEMBL8779795

ClC(Cl)Sc1ccc(SC(Cl)Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MMP2 P08253 1/20 0.36
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
MMP1 P03956 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779780 0.91 NR1H2 (0.41) CYP2C9CYP2C19HSD17B10MMP2MMP8
SCHEMBL3896041 0.88 HSD17B10 (0.52) CYP2C9CYP2C19HSD17B10MMP2MMP8
SCHEMBL3901375 0.86 HPGD (0.43)
SCHEMBL8779807 0.86 CYP2A6 (0.42) CYP2C9CYP2C19HSD17B10
SCHEMBL9018796 0.86 NR1H2 (0.50) CYP2C9CYP2C19HSD17B10MMP2MMP8
SCHEMBL8488661 0.86 IDO1 (0.39) CYP2C9CYP2C19HSD17B10MMP2MMP8
SCHEMBL3911663 0.84 SMN1; SMN2 (0.45) CYP2C9CYP2C19HSD17B10
SCHEMBL14894782 0.82 SMN1; SMN2 (0.43) CYP2C9CYP2C19HSD17B10
SCHEMBL8779800 0.82 MAOA (0.45) HSD17B10MMP8
SCHEMBL9018817 0.80 MEN1 (0.50) CYP2C9CYP2C19HSD17B10MMP2MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP disclosed
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed