Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779795 | 0.91 | CYP2C9 (0.37) | CYP2C9CYP2C19HSD17B10MMP2MMP8 | |
| SCHEMBL8779800 | 0.90 | MAOA (0.45) | NR1H2CYP3A4TSHRMAPK1MAOA | |
| SCHEMBL8484321 | 0.81 | CHRNA7 (0.39) | CYP3A4MAPK1MAOAMAOBHPGD | |
| SCHEMBL3896041 | 0.80 | HSD17B10 (0.52) | CYP3A4TSHRMAPK1MAOAMAOB | |
| SCHEMBL8779807 | 0.78 | CYP2A6 (0.42) | MAPK1MAOAMAOBCYP2C9CYP2C19 | |
| SCHEMBL3901375 | 0.78 | HPGD (0.43) | TSHRMAPK1LMNAHPGDL3MBTL1 | |
| SCHEMBL9018796 | 0.78 | NR1H2 (0.50) | NR1H2CYP3A4TSHRLMNAHPGD | |
| SCHEMBL8488661 | 0.78 | IDO1 (0.39) | CYP2C9CYP2C19HSD17B10MMP2MMP8 | |
| SCHEMBL3911663 | 0.77 | SMN1; SMN2 (0.45) | CYP3A4TSHRMAPK1MAOAMAOB | |
| SCHEMBL14894782 | 0.74 | SMN1; SMN2 (0.43) | CYP3A4TSHRMAPK1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770599-A1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |