Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490467 | 0.88 | CHRM3 (0.44) | ADRB2LMNAKMT2A | |
| SCHEMBL8491305 | 0.88 | CHEK2 (0.47) | ADRB2ALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL8490356 | 0.88 | KDM2B (0.51) | ALDH1A1KDM4EKMT2ANPC1NPSR1 | |
| SCHEMBL8486890 | 0.88 | ESR1 (0.52) | ADRB2HRH3MEN1KMT2APOLB | |
| SCHEMBL8490502 | 0.84 | CHEK2 (0.53) | ACHE | |
| SCHEMBL8489816 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL6600800 | 0.79 | ESR1 (0.61) | — | |
| SCHEMBL7502103 | 0.79 | NPC1 (0.66) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL8490051 | 0.77 | ESR1 (0.47) | SSTR5 | |
| SCHEMBL8492168 | 0.76 | ESR1 (0.54) | ALDH1A1KDM4EKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015521-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-04-01 | — | — | WO | disclosed |