SCHEMBL8490356 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KDM2B	Q8NHM5	12/20	0.51

▸	ESR1	P03372	2/20	0.41

▸	KMT2A	Q03164	1/20	0.41

▸	NPC1	O15118	1/20	0.40

▸	KDM4E	B2RXH2	2/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	GAA	P10253	1/20	0.40

▸	MAPT	P10636	1/20	0.40

▸	NPSR1	Q6W5P4	1/20	0.40

▸	TDP1	Q9NUW8	1/20	0.40

▸	CHEK2	O96017	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8492168	0.89	ESR1 (0.54)	KDM2BESR1KDM4EALDH1A1CHEK2
SCHEMBL8488729	0.88	ADRB2 (0.46)	KDM2BKMT2ANPC1KDM4EALDH1A1
SCHEMBL8489816	0.87	ALDH1A1 (0.52)	KMT2ANPC1ALDH1A1CHEK2
SCHEMBL8491305	0.83	CHEK2 (0.47)	NPC1KDM4EALDH1A1MAPTCHEK2
SCHEMBL8490502	0.82	CHEK2 (0.53)	CHEK2
SCHEMBL6603461	0.81	ESR1 (0.63)	ESR1
SCHEMBL8490467	0.79	CHRM3 (0.44)	ESR1KMT2A
SCHEMBL8487389	0.77	CHRNB2 (0.46)	KDM2BESR1NPC1ALDH1A1CHEK2
SCHEMBL8486890	0.76	ESR1 (0.52)	ESR1KMT2AGAA
SCHEMBL7502103	0.76	NPC1 (0.66)	KMT2ANPC1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999015521-A1	BENZOTHIOPHENES	ELI LILLY AND COMPANY (US)	1999-04-01	—	—	WO	disclosed