Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372589 | 0.88 | MAPK14 (0.49) | MAPK14FABP4FABP5PTGER1CSNK1D | |
| SCHEMBL20271796 | 0.83 | FABP4 (0.51) | MAPK14FABP4FABP5PTGER1CSNK1D | |
| SCHEMBL4426392 | 0.82 | MAPK14 (0.52) | MAPK14FABP4FABP5PTGER1CSNK1D | |
| SCHEMBL5079652 | 0.81 | MAPK14 (0.59) | MAPK14PTGER1CSNK1DALOX5DHODH | |
| SCHEMBL4422522 | 0.81 | MAPK14 (0.59) | MAPK14PTGER1CSNK1DALOX5DHODH | |
| SCHEMBL7445283 | 0.79 | MAPK14 (0.58) | MAPK14FABP4FABP5PTGER1CSNK1D | |
| SCHEMBL5488832 | 0.78 | FABP4 (0.49) | MAPK14FABP4FABP5PTGER1MAPK13 | |
| Formic Acid SCHEMBL27372078 | 0.77 | FABP4 (0.51) | MAPK14FABP4FABP5PTGER1CSNK1D | |
| SCHEMBL17265009 | 0.76 | FABP4 (0.53) | MAPK14FABP4FABP5PTGER1KDM4E | |
| SCHEMBL9961397 | 0.75 | NSD3 (0.55) | MAPK14PTGER1CSNK1DALOX5NSD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916891-A | CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686455-A | Imidazole derivatives and their use as cytokine inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |